June 22, 2024

Is CBD more effective on an empty stomach?

4 min read
CBD more effective

Over the years, CBD has gotten a good rap amongst people suffering from joint pain, body aches, etc. It has even helped people suffering from the symptoms of major physical and mental ailments. However, the one thing that most people focus on is the quality of CBD. Undoubtedly, it is equally important but more than that one also needs to have some understanding of the bioavailability of CBD. In other words, the amount of CBD that our body uses. If you are consuming CBD for the first time, taking CBD can be a bit intimidating. For example, how often are you supposed to take it? How should you consume it and can you take CBD on an empty stomach? All such pertinent questions are answered here in this post.

What is Bioavailability? 

Bioavailability is defined as “the extent to which a medicine or other substance is absorbed or becomes available at the site of physiological activity after delivery” by the American Heritage Medical Dictionary. In other words, how CBD is ingested affects how much of it is absorbed by the body and where it is distributed. When looking for CBD-based products, it’s critical for customers to comprehend this in order to choose which ones are best for them. Depending on how you take it, CBD will have a varied impact on you. Finding the approach that works for you is crucial when starting your CBD adventure. 

Should I take my CBD with or without food? 

When someone ingests CBD, in its purest form, less than 10% gets into their bloodstream. Researchers from the University of Minnesota’s department of pharmacology have looked at how eating a meal affects the absorption of CBD.

Fasting: Fasting alters how well your body can absorb CBD, but it also reduces variability when people take CBD in the morning before eating.

After food: Taking CBD oil after food increases the likelihood that it will have the best bioavailability possible. Given that the majority of the CBD oil’s effects were already absorbed sublingually, swallowing it increases the likelihood that it will be absorbed by the liver when the food in your stomach is already being digested. When you are full, CBD will stay in your system longer and have more time to work its magic. Taking CBD 30 minutes after a meal high in healthy fats increased people’s exposure to CBD by almost 5 times. When participants ate first, the peak plasma concentration of CBD was 14x higher. This implies that consuming food before taking CBD may lower the dosage necessary.

What should I take CBD with?

The meal you eat right before using CBD oil could also affect how well the rest of your body absorbs it. The best way to bind CBD and other cannabinoids is through the consumption of medium-chain and long-chain fatty acids, which are then more quickly and directly digested by the liver. Even though first-pass metabolism may still exist, it can be reduced with the correct ingredients, boosting bioavailability. Olive oil, sesame oil, soybean oil, and coconut oil are all recommended to take CBD with.

Important Note 

After taking your initial dose, pay attention to how you are feeling throughout the day. It’s important to keep in mind that various consuming methods operate in various ways. Here is a general estimate of how long CBD will take depending on the form,

  • The effects of vaping CBD typically start to kick in within a few minutes.
  • The average time it takes for sublingual oils (tinctures) to start working is 20 minutes.
  • It can take up to two hours for capsules and edibles to start working.
  • Topicals might take anywhere between minutes and hours to take effect, depending on the added ingredients.


First and foremost, it’s crucial never to consume CBD oil on an empty stomach. There are a number of reasons why it’s best to take cbd oil online India with food in your system, not just one. Although you can take it right away before or after eating, we definitely advise taking it after.

Bioavailability shouldn’t be a major concern for people who are just getting started with CBD. Our advice and best practice is to microdose CBD when you first begin using it. Start with a low dosage and instead of taking it in a single dose, it is better to take it multiple times throughout the day or night. Lastly, it might seem overwhelming, to try to understand the dosage to see effective results with CBD. Fret not and get in touch with a company that provides online medical consultation. Hempstrol is one such company that provides online medical consultations to its users. All you need to do is take an online appointment and their cannabis-certified doctors will take into consideration your health and any ailments you are suffering from to come up with a dosage of cannabis product or any other CBD products meant for your body.

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